Powder: -20°C for 3 years | In solvent: -80°C for 1 year
LSN2839567 (Abemaciclib metabolite M2) is the active metabolite of Abemaciclib, a potent CDK4 and CDK6 inhibitor (IC50s: 1-3 nM) with anticancer activity.LSN2839567 inhibits CDK9.LSN2839567 inhibits cell growth and cell cycle progression in a concentration-dependent manner. cell growth and cell cycle progression in a concentration-dependent manner and can be used to study breast and lung cancer.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 52.00 | |
5 mg | In stock | $ 123.00 | |
10 mg | In stock | $ 198.00 | |
25 mg | In stock | $ 439.00 | |
50 mg | In stock | $ 646.00 |
Description | LSN2839567 (Abemaciclib metabolite M2) is the active metabolite of Abemaciclib, a potent CDK4 and CDK6 inhibitor (IC50s: 1-3 nM) with anticancer activity.LSN2839567 inhibits CDK9.LSN2839567 inhibits cell growth and cell cycle progression in a concentration-dependent manner. cell growth and cell cycle progression in a concentration-dependent manner and can be used to study breast and lung cancer. |
Targets&IC50 | CDK6:1-3 nM, CDK4:1-3 nM |
In vivo | Abemaciclib metabolite M2 is a plasma metabolite of Abemaciclib with anticancer activity[2]. |
Synonyms | Abemaciclib metabolite M2 |
Molecular Weight | 478.54 |
Formula | C25H28F2N8 |
CAS No. | 1231930-57-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 1 mg/mL (2.09 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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LSN2839567 1231930-57-6 Cell Cycle/Checkpoint CDK Abemaciclib Metabolites M2 Abemaciclib metabolite M-2 Abemaciclib metabolite M2 inhibitor inhibit